Which blood tests might your doctor check while you are on Wegovy, Ozempic or Zepbound? Here is a plain-language list of common labs and why they matter.
| Test | Why it might be checked |
|---|---|
| A1c / fasting glucose | Blood sugar, especially with diabetes or prediabetes |
| Kidney function (creatinine, eGFR) | Dehydration from vomiting or diarrhea can affect kidneys |
| Lipid panel | Cholesterol often changes with weight |
| Liver tests | Fatty liver and gallbladder concerns |
| Ferritin / iron | Hair shedding, heavy periods, fatigue |
| Thyroid (TSH) | Tiredness, feeling cold, cycle changes |
| Vitamin B12 | Especially if you also take metformin |
| Vitamin D | Bone health in midlife |
| Pregnancy test | Before starting, if you could be pregnant |
This is a conversation starter, not a recommended panel. There is no guideline that sets a standard set of blood tests for being on a GLP-1 — which tests make sense depends on your history, your other medicines and what you’re being treated for. Your prescriber decides, and may well order none of these.
Log key numbers over time, like A1c, cholesterol and ferritin. Seeing trends next to your dose history makes follow-ups more useful.
Your prescriber decides based on your history. Many check a baseline.
Dehydration from vomiting or diarrhea can. Staying hydrated helps protect them.
Low B12 is a known effect of metformin, which some people take with GLP-1s.