Feeling cold on a GLP-1: is it normal?

Always cold since starting Ozempic or Zepbound? Here is why eating less and weight loss can make you feel colder, and when it is worth a check.

Why you might feel colder

Reason	Why
Eating less	Your body produces less heat from digestion
Less body fat	Fat insulates
Low iron	Can make you feel cold and tired
Thyroid	An underactive thyroid causes cold intolerance
Dehydration	Can affect circulation

What helps

layers, warm socks and a hat in winter
warm drinks and soups
regular meals, even small ones
movement through the day

When to get checked

MedlinePlus lists thyroid problems and anemia among common causes of cold intolerance. See your doctor if you also have:

extreme tiredness
hair shedding for months
heavy periods (a risk for low iron)
constipation, dry skin, or weight gain you can’t explain

A real-life example

Tina, 45, had to wear a sweater in July on Zepbound. She also had heavy periods and was exhausted. Blood tests showed low iron. Treating it helped her energy, and she felt less cold.

Common questions

Does Ozempic lower your body temperature?

It isn’t a listed side effect, but eating less and losing fat can make you feel colder.

Should I get my thyroid checked?

If feeling cold comes with other symptoms, it’s worth asking.

Will it go away?

Many people adjust over time. Eating regularly helps.